Affiliation:
1. From the Division of Otolaryngology, Departments of Surgery and Pharmacology, Southern Illinois University School of Medicine, Springfield.
Abstract
Chronic sinusitis may arise from a variety of causes. Failure of mucociliary transport, nasal obstruction, and breakdown of the mucosal barrier are important mechanisms that may contribute to irreversible tissue pathologic changes in the paranasal sinuses. Diagnosis is usually made radiographically using plain films, polytomography, or computerized tomography. Medical treatment attacks underlying causes such as allergy or viscous mucus secretions. In addition to antibiotic therapy, management of the underlying medical problems, general prophylactic measures, immunologic reconstitution of specific immune deficiencies, and vaccine therapy when combined with surgical therapy are likely to help improve survival of the immunosuppressed patient with chronic sinusitis.
Subject
Otorhinolaryngology,Surgery
Cited by
7 articles.
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1. The effect of topical treatments for CRS on the sinonasal epithelial barrier;Rhinology journal;2017-06-01
2. Mechanisms of Glucocorticoid Action in Chronic Rhinosinusitis;Allergy, Asthma & Immunology Research;2015
3. Topical Steroid for Chronic Rhinosinusitis without Polyps;Otolaryngology–Head and Neck Surgery;2012-01-31
4. MEDICAL MANAGEMENT IN ADULTS;Immunology and Allergy Clinics of North America;1994-02
5. SINUSITIS;Immunology and Allergy Clinics of North America;1993-02