Provocation-Neutralization: A Two-Part Study Part I. The Intracutaneous Provocative Food Test: A Multi-Center Comparison Study-Reference-Cited by-同舟云学术

Provocation-Neutralization: A Two-Part Study Part I. The Intracutaneous Provocative Food Test: A Multi-Center Comparison Study

Published:1988-09 Issue:3 Volume:99 Page:263-271
ISSN:0194-5998
Container-title:Otolaryngology–Head and Neck Surgery
language:en
Short-container-title:Otolaryngol Head Neck Surg

Author:

King William P.¹,Rubin Wallace A.²,Fadal Richard G.³,Ward Walter A.⁴,Trevino Richard J.⁵,Pierce William B.⁶,Stewart J. Alan⁷,Boyles John H.⁸

Affiliation:

1. Department of Otolaryngology and Communication Sciences, Baylor College of Medicine, Corpus Christi

2. Department of Otorhinolaryngology and Biocommunication, Louisiana State University School of Medicine

3. Department of Immunology, Holy Name Hospital

4. Winston-Salem

5. Oak Knowl Naval Hospital

6. Genesee Memorial Hospital, Batavia

7. Lake Jackson

8. Children's Medical Center and St. Elizabeth Medical Center and Wright State University

Abstract

This study investigated the clinical usefulness of the intracutaneous provocative-neutralization food test (IPFT). Thirty-seven patients were tested for five identical food allergies by eight physicians in different geographical locations. Throughout the study, comparison was made between the IPFT when interpreted by skin response (IPFT SK) and when interpreted by symptom provocation (IPFT PR). Double-blind IPFT results were compared with those of previously accomplished oral challenge food tests (OCFT). IPFT reliability was determined by a double-blind comparison of the initial IPFT, with two subsequent IPFTs performed 7 days apart. Correlation of the IPFT SK and IPFT PR with the OCFT provided validity coefficients of 0.78 and 0.61 respectively, both significant beyond the 0.01 level of confidence. Reliability of the IPFT SK and IPFT PR was shown to be 0.68 and 0.40, respectively. The IPFT SK was significant beyond the 0.01 level of confidence and the IPFT PR was significant beyond the 0.05 level of confidence.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

Link

http://journals.sagepub.com/doi/pdf/10.1177/019459988809900301

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