The Diabetes Prevention Program: headline results-Reference-Cited by-同舟云学术

The Diabetes Prevention Program: headline results

Published:2001-08 Issue:1 Volume:1 Page:62-64
ISSN:1474-6514
Container-title:The British Journal of Diabetes & Vascular Disease
language:en
Short-container-title:Diabetes & Vascular Disease

Author:

Bailey Clifford J¹

Affiliation:

1. Diabetes Group, School of Pharmacy, Aston University, Birmingham, B4 7ET,

Abstract

The Diabetes Prevention Program (DPP) was a trial of over 3,000 people with impaired glucose tolerance (IGT) to assess the effect of different interventions on their progression to type 2 diabetes. During an average follow-up period of three years, intensive lifestyle intervention with regular exercise and weight loss reduced the risk of progression to type 2 diabetes by 58%. Treatment with the antihyperglycaemic agent metformin reduced progression to type 2 diabetes by 31%. The DPP has therefore confirmed that rigorous lifestyle management can reduce the risk of type 2 diabetes and also shown that metformin therapy can reduce diabetes risk.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/14746514010010011001

Reference14 articles.

1. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

2. The Diabetes Prevention Program. Design and methods for a clinical trial in the prevention of type 2 diabetes.

3. Insulin resistance as the major cause of impaired glucose tolerance: a self-fulfilling prophesy?

4. Impaired Glucose Tolerance in the U. S. Population

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