Insulin-like growth factor binding protein-1 in insulin resistance and cardiovascular disease-Reference-Cited by-同舟云学术

Insulin-like growth factor binding protein-1 in insulin resistance and cardiovascular disease

Published:2012-01 Issue:1 Volume:12 Page:17-25
ISSN:1474-6514
Container-title:The British Journal of Diabetes & Vascular Disease
language:en
Short-container-title:Diabetes & Vascular Disease

Author:

Mehta Shweta¹,Livingstone Callum¹²,Borai Anwar³,Ferns Gordon⁴

Affiliation:

1. Department of Clinical Biochemistry, Royal Free Hospital, London, UK

2. Clinical Biochemistry Department, Royal Surrey County Hospital, Guildford, Surrey, UK

3. Clinical Biochemistry, Pathology Department, King Khalid National Guard Hospital, Kingdom of Saudi Arabia

4. Institute for Science and Technology in Medicine, Faculty of Health, University of Keele, Guy Hilton Research Centre, Stoke on Trent, Staffordshire UK

Abstract

Insulin-like growth factors (IGFs) are peptide hormones that have significant structural homology with insulin. IGF binding proteins (IGFBPs), in particular IGFBP-1, are important determinants of IGF activity such as enhancing peripheral glucose uptake, decreasing hepatic glucose output and modifying lipid metabolism. Herein factors which alter IGFBP-1 and the utility of measuring IGFBP-1 are considered as the role of IGFBP-1 is explored within the context of insulin resistance and the development of cardiovascular disease.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1474651412436701

Reference73 articles.

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