Feline maxillary sarcoma: clinicopathologic features of spindle cell sarcomas from the maxilla of 25 cats

Abstract

Case series summary Feline maxillary sarcomas are aggressive spindle cell neoplasms that occur within the maxilla, palate and upper lip of cats. This diagnosis includes fibrosarcoma and sarcomas with indeterminate histomorphology, excluding melanocytic tumors and sarcomas that can be differentiated by histomorphology. In this study of feline maxillary sarcomas in 25 cats, the cats’ ages ranged from 4 to 16 years (median 12.5). These sarcomas presented as smooth thickenings or mass lesions of the gingiva and palate, often involving both the right and left quadrants of the maxilla. Radiographic bone loss was typically absent to mild at the time of diagnosis. Histologically, feline maxillary sarcomas were composed of spindle cells with varying amounts of fibrous stroma and mild inflammation. Metastasis was not documented for any cat in the study, although clinical staging was limited. Cats were often euthanized because of local recurrence following incomplete tumor excision and local tumor progression. Median survival time from the date of histologic diagnosis was 70 days (n = 12). Relevance and novel information Feline maxillary sarcomas are aggressive neoplasms that may be difficult to differentiate from a benign, reactive process or other types of spindle cell neoplasms. Our findings indicate that feline maxillary sarcoma has distinctive clinical and histopathologic features, and the information provided in this paper will facilitate early and specific diagnosis of this tumor.