Early Osteoarthritis Questionnaire (EOAQ): a tool to assess knee osteoarthritis at initial stage

Author:

Migliore Alberto1ORCID,Alekseeva Liudmila2,Avasthi Sachin R.3,Bannuru Raveendhara R.4,Chevalier Xavier5,Conrozier Thierry6,Crimaldi Sergio7,de Campos Gustavo C.8,Diracoglu Demirhan9,Gigliucci Gianfranco10,Herrero-Beaumont Gabriel11ORCID,Iolascon Giovanni12ORCID,Ionescu Ruxandra13,Jerosch Jörg14,Lains Jorge15,Maheu Emmanuel16,Makri Souz17,Martusevich Natalia18,Matucci-Cerinic Marco19,Pavelka Karen20,Petrella Robert J.21,Raman Raghu22,Tarantino Umberto23

Affiliation:

1. Rheumatology Unit, San Pietro Fatebenefratelli Hospital, Via Cassia 600- 00189, Rome, Italy

2. Department of Metabolic Diseases of Bone and Joints, VA Nasonova Research Institute of Rheumatology, Moscow, Russian Federation

3. Department of Emergency Medicine, Dr Ram Manohar Lohia Hospital, Lucknow, India

4. Centre for Treatment Comparison and Integrative Analysis Division of Rheumatology, Tufts Medical Centre, Boston, MA, USA

5. Unit of Rheumatology, Henri Mondor Hospital, Créteil, France

6. Service de Rhumatologie, Hôpital Nord Franche, Belfort, France

7. Chirurgia Ortopedica Mininvasiva e Nuove Tecnologie, Humanitas Research Hospital, Castellanza, Italy

8. Department of Orthopaedics and Traumatology, University of Campinas, São Paulo, Brazil

9. Department of Physical Medicine and Rehabilitation Division of Pain Medicine, Istanbul University, Istanbul, Turkey

10. Rheumatology Unit, San Pietro Fatebenefratelli Hospital, Rome, Italy

11. Joint and Bone Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain

12. Department of Medical and Surgical Specialties and Dentistry, University of Campania ‘L Vanvitelli’, Caserta, Italy

13. Department of Internal Medicine and Rheumatology Sf. Maria Hospital, University of Medicine and Pharmacy ‘Carol Davila’, Bucharest, Romania

14. Orthopaedic Department, Johanna Etienne Hospital, Neuss, Germany

15. Physical Rehabilitation Medicine Department, Rovisco Pais Medical and Rehabilitation Centre, Tocha, Portugal

16. Rheumatology Department, AP-HP, Saint-Antoine Hospital, Paris, France

17. EUPATI Graduate and Patient Advocate, Brussels, Belgium

18. Department of Rheumatology, Belorussian State Medical University, Minsk, Belarus

19. Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

20. Institute of Rheumatology, Prague, Czech Republic

21. Department of Family Medicine, School of Kinesiology University Western Ontario, Ontario, ON, Canada

22. Academic Department of Orthopaedics, Hull and East Yorkshire NHS Trust Castle Hill Hospital, Cottingham, UK

23. Department of Orthopaedics and Traumatology, ‘Policlinico Tor Vergata’ Foundation, Rome, Italy

Abstract

Background: Early stage of osteoarthritis (OA) is characterized by joint stiffness and pain as well as by subclinical structural changes that may affect cartilage, synovium, and bone. At the moment, the lack of a validated definition of early osteoarthritis (EOA) does not allow to make an early diagnosis and adopt a therapeutic strategy to slow disease progression. Also, no questionnaires are available to evaluate the early stage, and therefore this remains an unmet need. Objective: Therefore, the purpose of the technical experts panel (TEP) of ‘International Symposium of intra-articular treatment’ (ISIAT) was to create a specific questionnaire to evaluate and monitor the follow-up and clinical progress of patients affected by early knee OA. Design: The items for the Early Osteoarthritis Questionnaire (EOAQ) were identified according to the following steps: items generation, items reduction, and pre-test submission. Methods: During the first step, literature has been reviewed and a comprehensive list of items about pain and function in knee EOA was drafted. Then, during the ISIAT (5th edition 2019), the draft has been discussed by the board, which reformulated, deleted, or subdivided some of the items. After the ISIAT symposium, the draft was submitted to 24 subjects affected by knee OA. A score based on the importance and the frequency was created and the items with a score ⩾0.75 were selected. After intermediate evaluation made by a sample of patients, the second and final version of the questionnaire EOAQ was submitted to the whole board for final analysis and acceptance in a second meeting (29 January 2021). Results: After an exhaustive elaboration, the final version of the questionnaire contains two domains (Clinical Features and Patients Reported Outcome) with respectively 2 and 9 questions, for a total of 11 questions. Questions mainly explored the fields of early symptoms and patients reported outcomes. Marginally, the need of the symptoms treatment and the use of painkillers were investigated. Conclusions: Adoption of diagnostic criteria of early OA is strongly encouraged and a specific questionnaire for the whole management of the clinical features and patients’ outcome might really improve the evolution of OA in the early stages of the disease, when the treatment is expected to be more effective.

Publisher

SAGE Publications

Subject

Orthopedics and Sports Medicine,Rheumatology

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Association between the immune-inflammation indicators and osteoarthritis - NHANES 1999-2018;Osteoarthritis and Cartilage Open;2024-02

2. DMOADs and DMARDs in the treatment of patients with joint and spine diseases;FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology;2023-12-12

3. Treatment of rheumatic diseases. Different nosologies, common problems;Modern Rheumatology Journal;2023-04-22

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3