Rare glomerulopathy associated with renal extramedullary hematopoiesis in a patient with primary myelofibrosis: A case report

Author:

Mesgun Sami1ORCID,Grosser Daniel2,Oduro Kwadwo3,Wang Jing2,Elmi Adily1,Chang Richard4,Rashidi Arash5ORCID

Affiliation:

1. Department of Internal Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA

2. Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA

3. Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA

4. Department of Hematology and Oncology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA

5. Department of Nephrology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA

Abstract

Renal involvement in primary myelofibrosis (PMF) is rare. Clinically, glomerular disease associated with PMF and other forms of myeloproliferative neoplasm (MPN) is characterized by renal insufficiency and high proteinuria. Few studies have observed extramedullary hematopoiesis (EMH) and glomerulopathy associated with PMF. In this article, we report a rare case of PMF-related glomerulopathy with renal EMH in a patient who presented with renal dysfunction and heavy proteinuria.

Publisher

SAGE Publications

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