Case-based discussions in onco-nephrology

Abstract

Onco-nephrology encompasses a wide range of complex problems including nephrotoxicity from traditional chemotherapy and targeted therapies, paraneoplastic kidney diseases, tumor- or treatment-related microangiopathies and glomerulonephritis, and kidney injuries associated with dysproteinemia, among others. To bring these topics to life, we present a case-based discussion of clinicopathologic features that we have encountered in our daily practices. We hope these discussions of clinical presentation, kidney biopsy findings, underlying pathophysiology, and therapeutic considerations will provide insight into recognizing and treating this expanding spectrum of diseases.