Antiretroviral therapy achieved metabolic complete remission of hepatic AIDS related Epstein-Barr virus-associated smooth muscle tumor

Author:

Ara Takahide12ORCID,Endo Tomoyuki12,Goto Hideki12,Kasahara Kohei1,Hasegawa Yuta12,Yokoyama Shota12,Shiratori Souichi1,Nakagawa Masao1,Kuwahara Ken3,Takakuwa Emi3,Hashino Satoshi24,Teshima Takanori12

Affiliation:

1. Department of Hematology, Hokkaido University Faculty of Medicine, Sapporo, Japan

2. HIV infection Medical Support Center, Hokkaido University Hospital, Sapporo, Japan

3. Department of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan

4. Hokkaido University Health Care Center, Sapporo, Japan

Abstract

Epstein-Barr virus-associated smooth muscle tumor (EBV-SMT) is a rare mesenchymal tumor which occurs in immunocompromised patients. The immune status is an important factor in the treatment of EBV-SMTs, but the efficacy of antiretroviral therapy (ART) is not elucidated in acquired immune deficiency syndrome (AIDS) related EBV-SMTs. Here, we report the first successful case of a 29-year-old man with hepatic AIDS related EBV-SMT treated with ART solely. Positron emission tomography scan was useful for the evaluation of disease status. Recent advances in ART that enables to restore patient’s immune status rapidly may change the treatment strategy in AIDS related EBV-SMT.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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