Comparative analysis of two different types of intracorneal implants in keratoconus: A corneal tomographic study

Author:

Sedaghat Mohammad-Reza1,Momeni-Moghaddam Hamed23ORCID,Belin Michael W4,Piñero David P5,Akbarzadeh Reyhaneh3,Ambrósio Renato6ORCID,Hosseini Seyed Rafi2

Affiliation:

1. Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2. Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran

3. Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran

4. Department of Ophthalmology & Vision Science, University of Arizona, Tucson, AZ, USA

5. Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain

6. Department of Ophthalmology, Federal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil

Abstract

Objective: To evaluate changes in visual acuity and corneal tomographic outcomes at 6 months after femtosecond-laser assisted implantation of two different types of intracorneal implants in keratoconus. Methods: A total of 39 keratoconus eyes implanted with two segments KeraRing ( n = 22 eyes) or MyoRing ( n = 17 eyes) were enrolled. Tomographic data (Pentacam system, Oculus) were analyzed and correlated with enhancement in uncorrected (UDVA) and corrected distance visual acuity (CDVA). The tomographic indices were front maximum keratometry (Kmax), corneal asphericity (Q-value) on both surfaces, average pachymetric progression indices (PPI), maximum Ambrosio relational thickness (ARTmax), Belin-Ambrósio enhanced ectasia total deviation index (BAD-D), index of surface variance (ISV), vertical asymmetry (IVA), height asymmetry (IHA) and height decentration (IHD). Results: LogMAR UDVA and CDVA improved 2.1 ( p = 0.003) and 0.7 ( p = 0.074) lines with KeraRing, and 8 and 2.5 lines with MyoRing ( p = 0.001). The highest and lowest mean differences in the tomographic indices between both groups were related to ISV and IHD, respectively. Changes in all indices differed significantly between two groups except for changes in front corneal astigmatism, ARTmax, ISV, IVA, IHD and IHA ( p > 0.05). Correlation of changes in CDVA with changes in other parameters was statistically significant only for IHD in the KeraRing group, while changes in in UDVA were significantly correlated with changes in spherical equivalent, back Q-value, ISV, IVA, and IHA only in the MyoRing group. Conclusion: Both implants promote corneal shape regularization and an enhancement in UDVA in keratoconus. A considerable flattening effect and reduction in prolateness in the front corneal surface were observed with MyoRing.

Publisher

SAGE Publications

Subject

Ophthalmology,General Medicine

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