Ocular manifestations of COVID-19 in the pediatric age group

Author:

Alnahdi Muhannad A123ORCID,Alkharashi Maan456

Affiliation:

1. Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada

2. College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

3. Department of Ophthalmology, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia

4. Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia

5. Department of Ophthalmology, Boston Children's Hospital, Boston, Massachusetts

6. Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts

Abstract

The coronavirus disease 2019 (COVID-19) is now known to be associated with several ocular manifestations. The literature thoroughly discussed those that affect adults, with a lesser focus in the pediatric age group. We aim to outline the various pediatric ocular manifestations described in the literature. The manifestations may be divided into isolated events attributed to COVID-19 or occurring in the new multisystem inflammatory syndrome in children (MIS-C), a novel entity associated by COVID-19 infection. Ocular manifestations have virtually affected all ages. They manifested in neonates, infants, children, and adolescents. Episcleritis, conjunctivitis, optic neuritis, cranial nerve palsies, retinal vein occlusion, retinal vasculitis, retinal changes, orbital myositis, orbital cellulitis were reported in the literature with this emerging viral illness. Conjunctivitis was the most common ocular manifestation in MIS-C in nearly half of the patients. Other ocular manifestations in MIS-C were anterior uveitis, corneal epitheliopathy, optic neuritis, idiopathic intracranial hypertension, and retinitis. The clinical outcome was favorable, and children regain their visual ability with minimal or no deficits in most of the cases. Further follow-up may be warranted to better understand the long-term effects and visual prognosis.

Publisher

SAGE Publications

Subject

Ophthalmology,General Medicine

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