Bilateral Serous Macular Detachment as a Presenting Feature of Acute Lymphoblastic Leukemia

Abstract

Purpose To report a case of bilateral serous maculopathy as an initial sign of acute lymphoblastic leukaemia in children. Methods/Results A 13-year-old girl, who presented with symptoms of visual blurring, was found to have a bilateral serous maculopathy. Haematological abnormalities (thrombocytopenia with a mild lymphocytosis) prompted further investigation. A bone marrow aspirate revealed the presence of leukemic blasts and a diagnosis of acute lymphoblastic leukaemia was made. Her maculopathy completely resolved following systemic chemotherapy. Conclusions Prompt recognition of disease led to early systemic treatment and restoration of visual function.