The effect of ocular dominance on macular function: A pattern electroretinogram study

Abstract

Purpose: To investigate the effect of ocular dominance on pattern electroretinogram (PERG) recordings in the participants who have no ophthalmic diseases. Methods: One hundred and twelve eyes of 56 participants (mean age 32.96 ± 10.82 years) were included in this prospective, cross-sectional study. After detailed ophthalmological examination and determination of the ocular dominance with hole-in-a-card test, the PERG was performed to determine implicit time and amplitudes of P50 and N95. Results: There were no significant interocular differences in visual acuity, refractive error, or intraocular pressure ( p > 0.05 for all). Thirty-six (64.3%) of the participants had ocular dominance in the right eye. The dominant eyes had significantly higher P50 amplitude than in the fellow nondominant eyes (6.90 µV in dominant vs 5.87 µV in nondominant; p = 0.015; 95% confidence interval). There was no significant difference in N95 amplitude, N95/P50 ratio, and implicit times of P50 and N95 between the dominant and nondominant eyes of the participants ( p = 0.090, p = 0.124 p = 0.817, p = 0.668; respectively). Conclusion: The analysis revealed a significantly increased P50 amplitude of the PERG, which is known to be highly associated with macular function, in dominant eyes of the patients when compared to fellow nondominant eyes.