Barium-induced toxic anterior segment syndrome

Author:

Matsushita Kenji1ORCID,Kawashima Rumi1,Hashida Noriyasu1,Hamano Yuki1,Harada Kazuo2ORCID,Higashisaka Kazuma2,Baba Koichi1,Sato Shigeru1,Huang Weiran1,Matsumoto Hiroshi2,Hamanaka Teruhiko34,Quantock Andrew J.5,Nishida Kohji16

Affiliation:

1. Department of Ophthalmology, Graduate School of Medicine, Osaka University, Osaka, Japan

2. Department of Legal Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan

3. Department of Ophthalmology, Japanese Red Cross Medical Center, Tokyo, Japan

4. Jyoetsu Ishida Eye Clinic, Niigata, Japan

5. School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, UK

6. Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan

Abstract

Toxic anterior segment syndrome (TASS) is a rapid-onset inflammation of the eye following uneventful ocular surgery. We report a case of TASS following Baerveldt glaucoma implant (BGI) surgery. Inductively coupled plasma-mass spectrometry (ICP-MS) identified barium in the eye and in the eluate from the bleb of the BGI. We attribute TASS in our patient to the dissolution of barium from the BGI and its entry into the eye, where it causes severe inflammation.

Funder

Japan Society for the Promotion of Science

Osaka University

Publisher

SAGE Publications

Subject

Ophthalmology,General Medicine

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