Fasting and Non-fasting Serum Amino Acid Values in three Home Parenteral Nutrition Patients: A Comparison between Synthamin 17R and Vamin N 7%R

Abstract

Serum amino acid concentrations were measured during the fasting and non-fasting stages of nutrition in three home parenteral nutrition patients who received their nitrogen requirement as Synthamin 17R for 12 months then Vamin N 7%R for 12 months. When the patients received Synthamin 17R, the fasting serum amino acid values revealed consistently elevated levels of glycine, phenylalanine, methionine and alanine and low levels of leucine, iso-leucine, valine, lysine, histidine, cystine and serine. When the patients received Vamin N 7%R, the fasting serum amino acid levels showed consistently elevated levels of proline, phenylalanine, glutamate, alanine, cystine and valine and low levels of arginine. Many of the serum amino acid abnormalities observed reflected the differences in the amino acid profiles of Vamin N 7%R and Synthamin 17R when compared with a normal diet.