Systemic Levels of 6-Keto-Prostaglandin F1α Following Administration of Inhaled Aerosolized Prostacyclin-Reference-Cited by-同舟云学术

Systemic Levels of 6-Keto-Prostaglandin F1α Following Administration of Inhaled Aerosolized Prostacyclin

Published:1997-12 Issue:6 Volume:25 Page:701-703
ISSN:0310-057X
Container-title:Anaesthesia and Intensive Care
language:en
Short-container-title:Anaesth Intensive Care

Author:

van Heerden P. V.¹

Affiliation:

1. Department of Intensive Care, Sir Charles Gairdner Hospital, Perth, W.A.

Abstract

A case is described where systemic levels of prostacyclin metabolite were measured during inhaled aerosolized prostacyclin (IAP) therapy for severe hypoxaemia in a patient with the acute respiratory distress syndrome. Comparable levels of prostacyclin metabolite have been associated with a marked platelet aggregation defect in vitro. A platelet aggregation defect was also demonstrated in vivo in this patient. Haemodynamic and gas exchange data during the IAP therapy are described.

Publisher

SAGE Publications

Subject

Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/0310057X9702500620

Reference8 articles.

1. Aerosolized Prostacyclin

2. Inhaled Aerosolized Prostacyclin as a Selective Pulmonary Vasodilator for the Treatment of Severe Hypoxaemia

3. Inhalation of prostacyclin (PGI2) for 8 hours does not produce signs of acute pulmonary toxicity in healty lambs

4. An Expanded Definition of the Adult Respiratory Distress Syndrome

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