Acute Respiratory Distress in a Bleomycin Primed Patient: A New Use for Nitric Oxide-Reference-Cited by-同舟云学术

Acute Respiratory Distress in a Bleomycin Primed Patient: A New Use for Nitric Oxide

Published:2007-02 Issue:1 Volume:35 Page:86-90
ISSN:0310-057X
Container-title:Anaesthesia and Intensive Care
language:en
Short-container-title:Anaesth Intensive Care

Author:

Holley A.¹,Cartner M.¹,Lipman J.¹²

Affiliation:

1. Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia

2. Department of Intensive Care Medicine and Burns, Trauma and Critical Care Research Centre, Royal Brisbane and Women's Hospital and The University of Queensland.

Abstract

We describe the use of nitric oxide as an oxygen-sparing strategy in the context of prior bleomycin exposure. A 27-year-old male, previously treated with bleomycin for a testicular germ cell tumour, presented with severe acute respiratory distress syndrome on the second postoperative day following an extensive retroperitoneal dissection. The mechanism of bleomycin toxicity and potential benefits of nitric oxide in this situation are considered.

Publisher

SAGE Publications

Subject

Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/0310057X0703500112

Reference27 articles.

1. Perioperative Considerations for Patients Treated with Bleomycin

2. Bleomycin-Induced Pneumonitis

3. Singlet oxygen production by bleomycin. A comparison with heme-containing compounds.

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