Door-to-Needle Time in Acute Stroke Treatment and the “July Effect”

Author:

Hawkes Maximiliano A.1,Carpani Federico2,Farez Mauricio F.34,Ameriso Sebastian F.2

Affiliation:

1. Division of Critical Care Neurology, Department of Neurology, Mayo Clinic, Rochester, MN, USA

2. Department of Neurology, Raúl Carrea Institute for Neurological Research (FLENI), Buenos Aires, Argentina

3. Center for Research on Neuroimmunological Diseases (CIEN), Raúl Carrea Institute for Neurological Research (FLENI), Buenos Aires, Argentina

4. Center of Biostatistics, Epidemiology and Public Health (CEBES), Raúl Carrea Institute for Neurological Research (FLENI), Buenos Aires, Argentina

Abstract

Intravenous thrombolysis improves outcomes in acute ischemic stroke in a time-dependent fashion. As in teaching hospitals, clinical outcomes may worsen due to the arrival of new inexperienced house staff early in the academic year (July effect, JE), we evaluated the impact of the “JE” on the door-to-needle time for intravenous thrombolysis and other stroke outcomes. In this retrospective cohort study, we assessed all acute ischemic strokes treated with intravenous thrombolysis between July 2003 and June 2016. Among 101 patients, there was no detrimental July effect on the door-to-needle time, rate of thrombolysis within 60 minutes of arrival, thrombolysis of stroke mimics, post-thrombolysis intracranial hemorrhages, National Institutes of Health Stroke Scale, and modified Rankin Scale outcomes.

Publisher

SAGE Publications

Subject

Clinical Neurology

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