Nature and Treatment Received for Psoriasis and Co-morbidities in Patients with Psoriatic Arthritis. A Multi-centre Observational Study from Western India

Author:

Kadam Soham1,Jadhav Praveen2,Shaikh Asna3,Shinde Sushant4,Bagul Varsha5,Oak Jyotsna6,Nolkha Nilesh7,Balakrishnan C.8,Mehta Priti Nagnur9,Kalke Shubhada10,Bhojani Kaushik10,Samant Rohini8

Affiliation:

1. Hinduja National Hospital and MRC, Veer Savarkar Marg, Mumbai, Maharashtra, India

2. Omkar Rheumatology Clinic, Nashik, Maharashtra, India

3. Hinduja National Hospital and Medical Research Center, Mumbai, Maharashtra, India

4. Quest Clinic, Mumbai, Maharashtra, India

5. Bombay Hospital, Mumbai, Maharashtra, India

6. Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra, India

7. Nirjara Multispeciality Clinic, Mumbai, Maharashtra, India

8. P. D. Hinduja Hospital and MRC, Mumbai, Maharashtra, India

9. Rheumed Speciality Clinic, Mumbai, Maharashtra, India

10. Kennisha Rheumatology Care and Diagnostics, Mumbai, Maharashtra, India

Abstract

Background: Many recent studies have suggested a changing paradigm of management of psoriatic disease. One of the main concerns is the lost opportunity of controlling ‘psoriatic disease’ during the early phase, especially when the disease is limited to the skin. Objective: The study’s main aim was to determine psoriasis (PsO) treatment before the patient’s presentation to the rheumatologist. We also studied the associated comorbidities in these patients. Methods: This was a cross-sectional study done at eight centres. Data was collected from 375 patients with psoriatic arthritis (PsA) about their demography, details of psoriatic lesions, treatment taken for them, additional co-morbidities and pattern of PsA. Results: Only 22.4% of patients had received oral methotrexate for PsO: the majority for less than a year. Plaque and scalp PsO were the most common, and 75% of patients had body surface area involvement greater than 5%. There was a significantly higher prevalence of type II diabetes mellitus (T2DM) (24% vs. 9.1%) and obesity as compared to the general population. Conclusion: Few patients received sustained systemic treatment for PsO prior to the development of arthritis. There was a significant association of co-morbidities such as T2DM and obesity with PsA.

Publisher

SAGE Publications

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