Peritoneal Dialysis Prescription for Neonates

Author:

Fischbach Michel1

Affiliation:

1. Nephrology Dialysis Transplantation Children's Department, Hôpital de Hautepierre, Strasbourg, France

Abstract

Despite the major advances in the management of renal failure, the mortality and morbidity rates remain higher in neonates than in older children. But, in most of the cases, effective peritoneal dialysis is possible, giving these neonates a chance of life. In infants and neonates, peritoneal permeability seems to be in a hyperpermeable state, perhaps only related to the volume of the instilled dialysate. Practical peritoneal prescriptions in neonates have to be balanced between either short dwell times optimizing ultrafiltration or long dwell times optimizing the diffusive process and blood purification. The recommendations for peritoneal dialysis in neonates usually admitted are short dwell times, one hour or less, adapted to ultrafiltration need, and small instilled dialysate volumes, 10 20 mL/kg initially, to avoid raised intra-abdominal pressure. Age-related particular risks are hyponatremia and hypophosphatemia.

Publisher

SAGE Publications

Subject

Nephrology,General Medicine

Cited by 19 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Management of Peritoneal Dialysis in Children;Pediatric Kidney Disease;2023

2. Peritoneal dialysis in very low and extremely low birthweight infants: A pooled analysis;Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis;2021-12-07

3. ISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 Update (paediatrics);Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis;2021-02-01

4. End-stage kidney disease in infancy: an educational review;Pediatric Nephrology;2018-11-21

5. Neonatal renal replacement therapy: An ethical reflection for a crucial decision;Archives de Pédiatrie;2018-08

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