Prevention of Peritonitis in Children on Peritoneal Dialysis

Author:

Verrina Enrico1,Honda Masataka2,Warady Bradley A.3,Piraino Beth4

Affiliation:

1. G. Gaslini Children's Hospital, Genoa, Italy

2. Tokyo Metropolitan Children's Hospital, Tokyo, Japan

3. The Children's Mercy Hospital, Kansas City, Missouri

4. University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.

Abstract

We reviewed methods of preventing peritonitis in children. A considerable body of evidence indicates that peritonitis rates are lowest with the use of a double-cuffed catheter, with a downward directed tunnel, placed by an experienced surgeon. Evidence in adults, but lacking in children, suggests that exit-site mupirocin will lower Staphylococcus aureus exit-site infections and thus peritonitis rates. The risk of peritonitis due to contamination can be diminished by the avoidance of spiking and by the provision of a long training period. Catheter removal and replacement for catheter-related peritonitis may be done simultaneously in certain circumstances and is useful in decreasing the risk of recurrent peritonitis. Antibiotic prophylaxis at the time of catheter insertion, for contamination, during dialysate leaks, and for invasive procedures appears to be useful in diminishing peritonitis risk.

Publisher

SAGE Publications

Subject

Nephrology,General Medicine

Cited by 24 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Peritonitis;Principles and Practice of Pediatric Infectious Diseases;2018

2. Peritonitis in children with automated peritoneal dialysis: a single-center study of a 10-year experience;Renal Failure;2016-05-17

3. Two-stage estimation for multivariate recurrent event data with a dependent terminal event;Biometrical Journal;2014-12-18

4. Peritonitis;Principles and Practice of Pediatric Infectious Diseases;2012

5. Renal Functional Development and Diseases in Children;Campbell-Walsh Urology;2012

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