The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system

Author:

Talbot Benjamin123,Davies Simon45,Burman Jenny2,Ritchie Angus67,Snelling Paul8,Lynch Sue9,Park Youn8,Jones Brian68,Garvey Vincent12,Jaure Allison10,Jardine Meg1611,Perkovic Vlado13,Gallagher Martin112,Brandwood Arthur213,Kaur Navneet2,Knight John1237

Affiliation:

1. Renal and Metabolic Division, The George Institute for Global Health, University of New South Wales, Sydney, Australia

2. Ellen Medical Devices, Sydney, Australia

3. Faculty of Medicine and Health, University of New South Wales, Sydney, Australia

4. Renal Research Group, School of Medicine, Keele University, UK

5. Renal Department, University Hospital of North Staffordshire NHS Trust, Stoke-on-Trent, UK

6. Concord Repatriation General Hospital, Sydney, Australia

7. Faculty of Medicine and Health, The University of Sydney, Australia

8. Renal Unit, Royal Prince Alfred Hospital, Sydney, Australia

9. MedTech Pathways, Sydney, Australia

10. Sydney School of Public Health, The University of Sydney, Australia

11. NHMRC Clinical Trials Centre, The University of Sydney, Australia

12. South Western Sydney Clinical School, University of New South Wales, Sydney, Australia

13. School of Biomedical Engineering, University of Sydney, Australia

Abstract

The global unmet need for kidney replacement therapy means that millions of people die every year as they cannot afford treatment. Peritoneal dialysis (PD) offers comparable survival to haemodialysis and is often more affordable, but one barrier to increasing access is that conventional manufacturing and distribution of PD fluid is costly. Here we report the results from a pilot proof-of-principal study demonstrating for the first time that the Ellen Medical Devices Point-of-Care system can be used by patients to produce sterile PD fluid at the point-of-care. With further development, this low-cost system could offer a solution to the many millions of people around the world who currently cannot afford treatment for kidney failure.

Publisher

SAGE Publications

Subject

Nephrology,General Medicine

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