Peritoneal Absorption of Vancomycin during and after Resolution of Peritonitis in Continuous Ambulatory Peritoneal Dialysis (CAPO) Patients-Reference-Cited by-同舟云学术

Peritoneal Absorption of Vancomycin during and after Resolution of Peritonitis in Continuous Ambulatory Peritoneal Dialysis (CAPO) Patients

Published:1988-04 Issue:2 Volume:8 Page:135-136
ISSN:0896-8608
Container-title:Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
language:en
Short-container-title:Perit Dial Int

Author:

Bastani B.¹,Spyker D. A.¹,Westervelt F. B.¹

Affiliation:

1. Divisions of Nephrology and Clinical Pharmacology, Department of Medicine, University of Virginia Hospitals, Charlottesville, Virginia

Abstract

We studied the absorption of i.p. loading dose of vancomycin (30 mg/kg of body weight) in five continuous ambulatory peritoneal dialysis (CAPD) patients, both at the time of peritonitis and after its resolution. Mean vancomycin absorption after 6 h of i.p. dwell was 74% from inflamed and 51% from noninflamed peritoneum. Mean peritoneal absorption half-life of vancomycin was 3.2 and 7.2 h in the inflamed vs. non inflamed peritoneum, respectively.

Publisher

SAGE Publications

Subject

Nephrology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/089686088800800205

Reference5 articles.

1. Treatment of Gram-Positive Peritonitis with Two Intraperitoneal Doses of Vancomycin in Continuous Ambulatory Peritoneal Dialysis Patients

2. Nonlinear least-squares regression programs for microcomputers

3. Vancomycin kinetics during continuous ambulatory peritoneal dialysis

4. Peritoneal Transport of Vancomycin in 4 Patients Undergoing Continuous Ambulatory Peritoneal Dialysis

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