Trends in age- and sex-specific prevalence and incidence of cardiovascular disease in Western Australia

Author:

Sarink Danja12,Nedkoff Lee3,Briffa Tom3,Shaw Jonathan E14,Magliano Dianna J14,Stevenson Christopher5,Mannan Haider6,Knuiman Matthew3,Hung Joseph7,Hankey Graeme J7,Norman Paul7,Peeters Anna148

Affiliation:

1. Baker IDI Heart and Diabetes Institute, Melbourne, Australia

2. Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany

3. School of Population and Global Health, The University of Western Australia, Perth, Australia

4. Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia

5. School of Health and Social Development, Faculty of Health, Deakin University, Melbourne, Australia

6. Translational Health Research Institute, School of Medicine, Western Sydney University, Australia

7. School of Medicine, The University of Western Australia, Perth, Australia

8. Deakin University, Geelong, Australia

Abstract

Background Temporal trends in incidence and mortality of cardiovascular disease (CVD) have been well described, with recent data suggesting declining improvements in those aged under 55 years. However, little is known about the combined impact of incidence and mortality trends on disease prevalence, an important indicator of disease burden and cost. We analysed changes in age-specific and age-standardised temporal trends in prevalence and incidence of CVD subtypes. Methods Annual prevalence and incidence rates of coronary heart disease, cerebrovascular disease and peripheral arterial disease for the Western Australian population for 1995–2010 were calculated using data from the Western Australian Data Linkage System. Joinpoint regression analyses were used to identify joinpoints in trends in age-specific and age-standardised annual prevalence and incidence rates for each CVD subtype. Results Between 1995 and 2010, age- and sex-specific incidence and prevalence of the CVD subtypes generally decreased among middle-aged and older adults, but were stable or increased among younger adults. In < 55 year olds, increases in incidence tended to occur from 2003, while increases in prevalence were from 2007/2008. Declines in age-standardised incidence were greater than those in crude incidence, with changes in population structure having a greater impact among men than women. Conclusions The majority of CVDs occurs in older adults. Our findings of generally worsening trends in prevalence in younger adults across most CVD subtypes were in contrast to generally declining trends in older age groups. These data highlight the importance of monitoring prevalence and incidence, particularly in younger adults.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Epidemiology

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