1. Pulmonary Vascular Group, Division of Respiratory Diseases, Department of Medicine, São Paulo School of Medicine (EPM), Federal University of Sao Paulo (UNIFESP), Brazil
2. Pulmonary Function and Clinical Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, São Paulo School of Medicine (EPM), Federal University of Sao Paulo (UNIFESP), Brazil
3. Division of Respiratory and Critical Care Medicine, Department of Medicine, Queeńs University, Kingston, Canada