1. Department of Cardiology, University Hospital Zurich, University Heart Center, University of Zurich, Rämistrasse 100, Zurich 8091, Switzerland
2. Department of Clinical Pharmacology, University Hospital Basel, Basel, Switzerland
3. Department of Cardiology, Geneva University Hospital, Geneva, Switzerland
4. Amgen Switzerland AG, Rotkreuz, Switzerland
5. Center for Observational Research, Amgen Inc., Thousand Oaks, CA, USA
6. International Biostatistics, Amgen Ltd, Uxbridge, UK
7. Medical Department, Amgen Ltd, Uxbridge, UK
8. Imperial Centre for Cardiovascular Disease Prevention and Imperial Clinical Trials Unit, Imperial College London, London, UK