Adaptive designs from a Data Safety Monitoring Board perspective: Some controversies and some case studies-Reference-Cited by-同舟云学术

Adaptive designs from a Data Safety Monitoring Board perspective: Some controversies and some case studies

Published:2017-02-09 Issue:5 Volume:14 Page:462-469
ISSN:1740-7745
Container-title:Clinical Trials
language:en
Short-container-title:Clinical Trials

Author:

Turnbull Bruce W¹

Affiliation:

1. School of Operations Research and Information Engineering, Cornell University, Ithaca, NY, USA

Abstract

This article describes vignettes concerning interactions with Data Safety Monitoring Boards during the design and monitoring of some clinical trials with an adaptive design. Most reflect personal experiences by the author.

Publisher

SAGE Publications

Subject

Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1740774516689261

Reference38 articles.

1. Twenty‐five years of confirmatory adaptive designs: opportunities and pitfalls

2. Confirmatory Seamless Phase II/III Clinical Trials with Hypotheses Selection at Interim: Applications and Practical Considerations

3. Standardversus adaptive monitoring procedures: a commentary

4. Effects of Selenium Supplementation for Cancer Prevention in Patients With Carcinoma of the Skin

5. Reporting Conflicts of Interest, Financial Aspects of Research, and Role of Sponsors in Funded Studies

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