Covid-Associated Pulmonary Aspergillosis: Does Law of Parsimony Always Work in Resource-Limited Setting?

Author:

Vysakha Kavadisseril Vivekanandan1ORCID,Edakalavan Jyothi2,Rajappan Lakshmy3,O. Sasikumari4,Hameed Shahul1

Affiliation:

1. Department of Medicine, Government Medical College, Kollam, Kerala, India

2. Department of Respiratory Medicine, Government Medical College, Kollam, Kerala, India

3. Department of Pathology, Government Medical College, Kollam, Kerala, India

4. Department of Microbiology, Government Medical College, Kollam, Kerala, India

Abstract

Aspergillosis species of fungus causes invasive disease in the setting of immunocompromise. Of the various manifestations, invasive aspergillosis is the severest form and failure to timely identify and treat the infection will lead to mortality and morbidity. The difficult task is to isolate the pathogen and confirm the diagnosis as the criteria for the same are stringent. In the setting of severe COVID-19, this poses a risk, especially in a resource-limited setting. We report a case of Covid-associated pulmonary aspergillosis in a resource-limited setting which was confirmed by histopathologic. We would like to highlight that a high index of suspicion and evaluation in the right setting is necessary to identify the pathogen.

Publisher

SAGE Publications

Subject

General Medicine

Reference31 articles.

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3. Mohamed A, Hassan T, Trzos-Grzybowska M, Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: a lethal combination. Med Mycol Case Rep [Internet]. 2020 Jun [cited 2020 Aug 27]. https://linkinghub.elsevier.com/retrieve/pii/S2211753920300427. Accessed September 7, 2022.

4. Invasive pulmonary aspergillosis complicating COVID-19 in the ICU - A case report

5. COVID-19–associated Pulmonary Aspergillosis

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