Genetic Contributions to Acquired Epilepsies-Reference-Cited by-同舟云学术

Genetic Contributions to Acquired Epilepsies

Published:2020-09-29 Issue:1 Volume:21 Page:5-13
ISSN:1535-7597
Container-title:Epilepsy Currents
language:en
Short-container-title:Epilepsy Curr

Author:

Perucca Piero¹²³,Scheffer Ingrid E.⁴⁵⁶^ORCID

Affiliation:

1. Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia

2. Departments of Medicine and Neurology, The Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia

3. Department of Neurology, Alfred Health, Melbourne, Victoria, Australia

4. Department of Medicine, Epilepsy Research Centre, Austin Health, The University of Melbourne, Melbourne, Victoria, Australia

5. Department of Paediatrics, Royal Children’s Hospital, The University of Melbourne, Melbourne, Victoria, Australia

6. The Florey Neuroscience and Murdoch Children’s Research Institutes, Melbourne, Victoria, Australia

Abstract

Whether genetic factors contribute to acquired epilepsies has long been controversial. Supporters observe that, among individuals exposed to seemingly the same brain insult, only a minority develops unprovoked seizures. Yet, only in relatively recent years have studies started to build a case for genetic contributions. Here, we appraise this emerging evidence, by providing a critical review of studies published in the field.

Funder

Royal Australasian College of Physicians

National Health and Medical Research Council

Epilepsy Foundation

Publisher

SAGE Publications

Subject

Neurology (clinical)

Link

http://journals.sagepub.com/doi/pdf/10.1177/1535759720954254

Reference50 articles.

1. Incidence of unprovoked seizures and epilepsy in Iceland and assessment of the epilepsy syndrome classification: a prospective study