Towards a Rational Balanced Pancreatic and Islet Allocation Schema

Author:

Kandeel Fouad12,El-Shahawy Mohamed12,Singh Gagandeep3,Dafoe Donald C.4,Isenberg Jeffrey S.2ORCID,Riggs Arthur D.2

Affiliation:

1. Department of Translational Research & Cellular Therapeutics, City of Hope National Medical Center, Duarte, CA, USA

2. Arthur Riggs Diabetes & Metabolism Research Institute, City of Hope National Medical Center, Beckman Research Institute, Duarte, CA, USA

3. Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA

4. Department of Surgery, Division of Transplantation, University of California Irvine School of Medicine, Irvine, CA, USA

Abstract

Allocation of donated organs for transplantation is a complex process that considers numerous factors such as donor, organ and candidate characteristics and practical issues such as geography. Whole pancreas and isolated islet transplantation are lifesaving for certain individuals with diabetes. Herein, we suggest a revised allocation schema that matches donor characteristics with candidate medical condition while allowing for geographic considerations. It is hoped that adoption of this schema will shorten allocation time, decrease organ waste and optimize the parity between organ donor characteristics and candidate state of health.

Funder

Arthur Riggs Diabetes & Metabolism Research Institute

Publisher

SAGE Publications

Subject

Transplantation,Cell Biology,Biomedical Engineering

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