Cerebral Small Vessel Disease-Reference-Cited by-同舟云学术

Cerebral Small Vessel Disease

Published:2018-09-25 Issue:12 Volume:27 Page:1711-1722
ISSN:0963-6897
Container-title:Cell Transplantation
language:en
Short-container-title:Cell Transplant

Author:

Li Qian¹²,Yang Yang³²,Reis Cesar⁴,Tao Tao³,Li Wanwei¹,Li Xiaogang³,Zhang John H.⁴⁵^ORCID

Affiliation:

1. Department of Pediatrics, The Third Affiliated Hospital & Field Surgery Institution, Army Medical University, Chongqing, China

2. Both the authors contributed equally as co-authors.

3. Department of Neurology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China

4. Department of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA

5. Department of Anesthesiology, Loma Linda University School of Medicine, Loma Linda, CA, USA

Abstract

Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological processes and etiologies. Neuroimaging features of CSVD include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. The main clinical manifestations of CSVD include stroke, cognitive decline, dementia, psychiatric disorders, abnormal gait, and urinary incontinence. Currently, there are no specific preventive or therapeutic measures to improve this condition. In this review, we will discuss the pathophysiology, clinical aspects, neuroimaging, progress of research to treat and prevent CSVD and current treatment of this disease.

Publisher

SAGE Publications

Subject

Transplantation,Cell Biology,Biomedical Engineering

Link

http://journals.sagepub.com/doi/pdf/10.1177/0963689718795148

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