ATSDR evaluation of health effects of benzene and relevance to public health

Author:

Wilbur S1,Wohlers D2,Paikoff S2,Keith LS1,Faroon O1

Affiliation:

1. Agency for Toxic Substances and Disease Registry (ATSDR), U.S. Department of Health and Human Services, Atlanta, Georgia, USA

2. Syracuse Research Corporation, Syracuse, New York, USA

Abstract

As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These profiles comprehensively summarize toxicological and environmental information. This article constitutes the release of portions of the Toxicological Profile for Benzene. The primary purpose of this article is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective on the toxicology of benzene. It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on the relevance of toxicity and toxicokinetic data to public health.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Toxicology

Reference630 articles.

1. ACGIH (2006) Benzene. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH: American Conference of Governmental Industrial Hygienists.

2. THE DEVELOPMENT OF THE HUMAN BLOOD-CSF-BRAIN BARRIER

3. Significance of exposure to benzene and other toxic compounds through environmental tobacco smoke

4. Agency for Toxic Substances and Disease Registry (1995) National Exposure Registry Benzene Subregistry Baseline Technical Report. Atlanta, GA: U.S. Department of Health and Human Services. Agency for Toxic Substances and Disease Registry. PB95255766, 1–114.

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