Caffeine as a photoprotective agent for diminishing phototoxicity-Reference-Cited by-同舟云学术

Caffeine as a photoprotective agent for diminishing phototoxicity

Published:2010-07-14 Issue:10 Volume:26 Page:667-670
ISSN:0748-2337
Container-title:Toxicology and Industrial Health
language:en
Short-container-title:Toxicol Ind Health

Author:

Yim Tong Szeto ¹,Tong Henry HY²

Affiliation:

1. Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology Foundation, Avenida Wai Long, Taipa, Macau SAR, PR China, ,

2. School of Health Sciences, Macao Polytechnic Insititute, Macau SAR, PR China

Abstract

Skin whitening with Chinese herbal medicine has been used in ancient Asia. However, phototoxicity of the active ingredient limits the application. The modified comet assay was used in the current study to detect DNA crosslinking induced by phototoxicity. Result showed that caffeine at 5 µmol/L was able to reduce 5-methoxypsoralen-induced phototoxicity with ultraviolet C (UVC) exposure.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Toxicology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0748233710375947

Reference19 articles.

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2. Total Antioxidant Capacity of Teas by the Ferric Reducing/Antioxidant Power Assay

3. In vitro and in vivo Study of 5-Methoxypsoralen Skin Concentration after Topical Application

4. Caffeine as an antioxidant: inhibition of lipid peroxidation induced by reactive oxygen species

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