Use of Recombinant Factor VIIa for Major Elective Surgery in a Patient with Factor VII Deficiency, Retroperitoneal Fibrosis and Hydronephrosis

Author:

Cobos Everardo1,Keung Yi-Kong2,Akhter Saeed2,Jones Jeff1

Affiliation:

1. Division of Oncology/Hematology, Texas Tech University Health Sciences Center, Lubbock, Texas, U.S.A.

2. Department of Urology, Texas Tech University Health Sciences Center, Lubbock, Texas, U.S.A.

Abstract

We described a case of obstructive uropathy due to retroperitoneal fibrosis associated with congenital factor VII deficiency. Nephrectomy and ileoureter reconstruction was performed uneventfully using recombinant factor Vlla perioperatively. There was no excessive bleeding or thrombosis. Key Words: Recombinant factor Vlla-rFVlla-Retroperitoneal fibrosis-Factor VII deficiency.

Publisher

SAGE Publications

Subject

Hematology,General Medicine

Reference13 articles.

1. Roberts HR, Lefkowitz JB: Inherited disorders of prothrombin conversion. In: Colman RW, Hirsh J, Marder VJ, et al., eds, Hemostasis and Thrombosis. Basic Principles and Clinical Practice. 3rd ed. Philadelphia: J.B. Lippincott Company , 1994, p. 200-9.

2. IDIOPATHIC RETROPERITONEAL FIBROSIS ASSOCIATED WITH A COAGULATION DEFECT (FACTOR VII DEFICIENCY): REPORT OF A CASE AND REVIEW OF THE LITERATURE

3. Use of recombinant activated factor VII for treatment of a retropharyngeal hemorrhage in a hemophilic patient with a high titer inhibitor

4. Control of haemostasis with recombinant factor VIIa in patient with inhibitor to factor VIII

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