A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19-Reference-Cited by-同舟云学术

A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19

Published:2021-01 Issue: Volume:27 Page:107602962110517
ISSN:1076-0296
Container-title:Clinical and Applied Thrombosis/Hemostasis
language:en
Short-container-title:Clin Appl Thromb Hemost

Author:

Klein Mark¹²^ORCID,Dao Vinh¹^ORCID,Khan Fatima¹²

Affiliation:

1. Minneapolis Veterans Affairs Healthcare System, Minneapolis, MN, 55417, USA

2. University of Minnesota, MN, USA

Abstract

The precise mechanisms of pathology in severe COVID-19 remains elusive. Current evidence suggests that inflammatory mediators are responsible for the manifestation of clinical symptoms that precedes a fatal response to infection. This review examines the nature of platelet activating factor and emphasizes the similarities between the physiological effects of platelet activating factor and the clinical complications of severe COVID-19.

Publisher

SAGE Publications

Subject

Hematology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/10760296211051764

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