A Hierarchical Taxonomy of Psychopathology Can Transform Mental Health Research

Author:

Conway Christopher C.1ORCID,Forbes Miriam K.2,Forbush Kelsie T.3,Fried Eiko I.4ORCID,Hallquist Michael N.5,Kotov Roman6,Mullins-Sweatt Stephanie N.7,Shackman Alexander J.8,Skodol Andrew E.9,South Susan C.10,Sunderland Matthew11,Waszczuk Monika A.6,Zald David H.12,Afzali Mohammad H.13,Bornovalova Marina A.14,Carragher Natacha15,Docherty Anna R.16,Jonas Katherine G.6,Krueger Robert F.17,Patalay Praveetha18,Pincus Aaron L.5,Tackett Jennifer L.19,Reininghaus Ulrich2021,Waldman Irwin D.22,Wright Aidan G. C.23,Zimmermann Johannes24,Bach Bo25,Bagby R. Michael26,Chmielewski Michael27,Cicero David C.28,Clark Lee Anna29,Dalgleish Tim30,DeYoung Colin G.17,Hopwood Christopher J.31,Ivanova Masha Y.32,Latzman Robert D.33ORCID,Patrick Christopher J.34,Ruggero Camilo J.35,Samuel Douglas B.10,Watson David29,Eaton Nicholas R.36

Affiliation:

1. Department of Psychological Sciences, College of William & Mary

2. Centre for Emotional Health, Department of Psychology, Macquarie University

3. Department of Psychology, University of Kansas

4. Department of Psychology, University of Amsterdam

5. Department of Psychology, Pennsylvania State University

6. Department of Psychiatry, State University of New York

7. Department of Psychology, Oklahoma State University

8. Department of Psychology and Neuroscience and Cognitive Science Program, University of Maryland

9. Department of Psychiatry, University of Arizona

10. Department of Psychological Sciences, Purdue University

11. National Health and Medical Research Council Centre for Research Excellence in Mental Health and Substance Use, National Drug and Alcohol Research Centre, University of New South Wales

12. Department of Psychology, Vanderbilt University

13. Department of Psychiatry, University of Montreal

14. Department of Psychology, University of South Florida

15. Medical Education and Student Office, Faculty of Medicine, University of New South Wales

16. Department of Psychiatry, University of Utah

17. Department of Psychology, University of Minnesota

18. Institute of Psychology, Health and Society, University of Liverpool

19. Department of Psychology, Northwestern University

20. Department of Psychiatry and Psychology, Maastricht University

21. Centre for Epidemiology and Public Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King’s College London

22. Department of Psychology, Emory University

23. Department of Psychology, University of Pittsburgh

24. Department of Psychology, University of Kassel

25. Psychiatric Research Unit, Slagelse Psychiatric Hospital

26. Departments of Psychology and Psychiatry, University of Toronto

27. Department of Psychology, Southern Methodist University

28. Department of Psychology, University of Hawaii at Manoa

29. Department of Psychology, University of Notre Dame

30. Medical Research Council Cognition and Brain Sciences Unit, Cambridge, United Kingdom

31. Department of Psychology, University of California, Davis

32. Department of Psychiatry, University of Vermont

33. Department of Psychology, Georgia State University

34. Department of Psychology, Florida State University

35. Department of Psychology, University of North Texas

36. Department of Psychology, Stony Brook University

Abstract

For more than a century, research on psychopathology has focused on categorical diagnoses. Although this work has produced major discoveries, growing evidence points to the superiority of a dimensional approach to the science of mental illness. Here we outline one such dimensional system—the Hierarchical Taxonomy of Psychopathology (HiTOP)—that is based on empirical patterns of co-occurrence among psychological symptoms. We highlight key ways in which this framework can advance mental-health research, and we provide some heuristics for using HiTOP to test theories of psychopathology. We then review emerging evidence that supports the value of a hierarchical, dimensional model of mental illness across diverse research areas in psychological science. These new data suggest that the HiTOP system has the potential to accelerate and improve research on mental-health problems as well as efforts to more effectively assess, prevent, and treat mental illness.

Publisher

SAGE Publications

Subject

General Psychology

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