Sundown Syndrome in Severely Demented Patients with Probable Alzheimer's Disease

Author:

Little John T.1,Satlin Andrew1,Sunderland Trey1,Volicer Ladislav1

Affiliation:

1. Biological Psychiatry Branch (Dr. Little), NIMH, Bethesda, Maryland; Harvard Medical School and McLean Hospital (Dr. Satlin), Belmont, Massachusetts; Section On Geriatric Psychiatry, Laboratory of Clinical Science (Dr. Sunderland), NIMH, Bethesda, Maryland; and Boston University School of Medicine and E.N. Rogers Memorial Veterans Hospital (Dr. Volicer), Bedford, Massachusetts.

Abstract

A retrospective review of 71 patients with probable Alzheimer's disease was analyzed with respect to nursing evaluations of sundowning status (recurring confusion or agitation in the late afternoon or early evening). The prevalence of sundowning (including probable sundowners) was 24%. Sundowners and non-sundowners differed with regard to number of sedatives received daily, particularly chloral hydrate, and the number of days on the inpatient unit. There were no differences between sundowners and non-sundowners with respect to other types of medications, medical diagnoses, current age, age of onset of Alzheimer's disease, or Mini-Mental State Exam. Restlessness was the most common sundowning behavior, although multiple behavioral disturbances were seen. This survey suggests that the sundown syndrome is a common problem in severely demented Alzheimer's patients and requires further study.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Neurology (clinical)

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