Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy in Dementias

Abstract

This article reviews recent studies of magnetic resonance imaging and magnetic resonance spectroscopy in demen tia, including Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, idiopathic Parkinson's disease, Huntington's disease, and vascular dementia. Magnetic resonance imaging and magnetic resonance spec troscopy can detect structural alteration and biochemical abnormalities in the brain of demented subjects and may help in the differential diagnosis and early detection of affected individuals, monitoring disease progression, and evaluation of therapeutic effect. (J Geriatr Psychiatry Neurol 2001; 14:145-166).