Direct puncture Onyx embolization of a large calvarial metastasis with intracranial extension: Case report

Author:

Zhou Minerva H1ORCID,Dunn Gavin P234,Osbun Joshua W256,Cross DeWitte T25,Moran Christopher J25,Dacey Ralph G2,Kansagra Akash P256

Affiliation:

1. School of Medicine, Washington University, St. Louis, MO, USA

2. Department of Neurological Surgery, Washington University, St. Louis, MO, USA

3. Department of Pathology and Immunology, Washington University, St. Louis, MO, USA

4. Center for Human Immunology and Immunotherapy Programs, Washington University, St. Louis, MO, USA

5. Mallinckrodt Institute of Radiology, Washington University, St. Louis, MO, USA

6. Department of Neurology, Washington University, St. Louis, MO, USA

Abstract

We report a case of renal cell carcinoma (RCC) metastasis to the calvarium and describe a strategy for percutaneous embolization of hypervascular calvarial tumors with intracranial extension. An elderly patient with history of RCC presented with left-sided weakness. Imaging studies showed a large right frontoparietal calvarial mass with intra- and extracranial extension. The tumor was devascularized by direct puncture tumor embolization using Onyx 18, allowing subsequent operative resection without significant blood loss or the need for flap reconstruction of the scalp. Compared to more common endovascular approaches, direct-needle puncture embolization of transcalvarial masses may offer lower risk of injury to scalp vessels and underlying brain parenchyma.

Publisher

SAGE Publications

Subject

Immunology

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