Prehospital technologies for early stroke detection – A review

Author:

Agrawal Deepsha1,Dhillon Permesh2,Siow Isabel3,Lee Keng Siang4ORCID,Spooner Oliver5,Yeo Leonard6ORCID,Bhogal Pervinder7ORCID

Affiliation:

1. Department of Radiology, Oxford University Hospitals NHS Trust, Oxford, UK

2. Department of Interventional Neuroradiology, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK

3. Yong Loo Lin School of Medicine, National University of Singapore, Singapore

4. Bristol Medical School, University of Bristol, UK

5. Department of Stroke Medicine, The Royal London Hospital, Barts NHS Trust, London, UK

6. Division of Neurology, Department of Medicine, National University Health System, Singapore

7. Department of Interventional Neuroradiology, The Royal London Hospital, Barts NHS Trust, London, UK

Abstract

The rate of neural circuitry loss in a typical large vessel occlusion well emphasizes that ‘Time is Brain’. Every untreated minute in a large vessel ischaemic stroke results in loss of 1.9 million neurons and 13.8 billion synapses. As such, it is essential to optimize the flow-limiting steps in delivering the current standard of care. The current diagnostic model involves recognition of symptoms by patients, followed by access to Emergency Medical Services and subsequent physical examination and neuroimaging in the Emergency Department. With more than 50% of stroke patients using Emergency Medical Services as the first point of care contact, it can be deduced that the outcome of the ‘stroke chain of survival’ can be improved by addressing the bottleneck of prehospital stroke diagnosis. Here we present a review of the existing technologies.

Publisher

SAGE Publications

Subject

Immunology

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