Shear wave elastography in the characterization of renal cell carcinoma and angiomyolipoma

Author:

Keskin Zeynep1ORCID,Keskin Suat2ORCID

Affiliation:

1. Department of Radiology, Konya City Hospital, Konya, Turkey

2. Department of Radiology, Karatay School of Medicine, Medicana Hospital, Konya, Turkey

Abstract

Background Detection and characterization of renal lesions are common in daily clinical practice. Purpose To investigate the effectiveness of shear wave elastography (SWE), a novel radiological examination technique, in the characterization of renal masses. Material and Methods The study included a total of 68 patients (33 men, 35 women; mean age = 57.71 ± 12.08 years; age range = 19–83 years) who underwent SWE. SWE measurements were obtained at depths of 2–8 cm from the probe surface in two different positions from an analysis window of approximately 0.5 × 1.0 cm on ultrasound. The cutoff SWE was calculated for the differentiation of renal cell carcinoma (RCC) and angiomyolipoma (AML) by receiver operating characteristic (ROC) analysis. When the result was statistically significant, the sensitivity, specificity, accuracy, and positive and negative predictive values of the test were calculated. Results Mass-to-parenchyma SWE ratios of RCCs were significantly higher than those of AMLs ( P = 0.003). In ROC curve analysis, the SWE cutoff was 1.215 m/s to differentiate RCCs from AMLs. The area under the ROC curve was calculated as 0.74 (95% CI = 0.610–0.871, sensitivity = 70.7%, specificity = 70.6%, positive predictive value = 87.8%, negative predictive value = 44.4%). Conclusion The SWE technique is increasingly used and may be useful in distinguishing RCC and AML lesions, and especially clear cell and non-clear cell RCCs.

Publisher

SAGE Publications

Subject

Radiology, Nuclear Medicine and imaging,General Medicine,Radiological and Ultrasound Technology

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