Affiliation:
1. Department of Radiology, Qilu Hospital of Shandong University, Jinan, Shandong Province, PR China
2. Qilu University of Technology, Changqing District, Jinan, Shandong Province, PR China
Abstract
Background Cardiac magnetic resonance (CMR) is an established tool for detection of myocarditis. However, no comprehensive data for CMR based on the “Lake Louise” criteria in pediatric myocarditis exists to date. Purpose To evaluate the value of multi-parameter CMR in children with suspected acute (AMC) and chronic myocarditis (CMC). Material and Methods We examined 73 pediatric patients with clinically suspected AMC (n = 25) and CMC (n = 48). We compared them to 17 controls. All individuals underwent CMR, including function analyses, T2 ratio, early gadolinium enhancement ratio (EGEr), and late gadolinium enhancement (LGE). Results In AMC, 19 (76%) patients were abnormal in any two of three parameters (T2 ratio, EGEr, and LGE). There was a significant difference between AMC and controls in LVEF (51.2% vs. 61.3%), mass (130.2 ± 14.0 vs. 120.5 ± 13.9 g), T2 ratio (1.96 ± 0.2 vs. 1.69 ± 0.13), and EGEr (4.1 ± 0.27 vs. 3.4 ± 0.39) ( P < 0.05). In CMC, 26 (54.1%) patients were abnormal in any two of three parameters. There was no significant difference between CMC and controls in LVEF and mass, but there was a statistical difference in T2 ratio (1.88 ± 0.18 vs. 1.69 ± 0.13) and in EGEr (3.93 ± 0.22 vs. 3.4 ± 0.39) ( P < 0.05). There was an increase in LVEF while both T2 ratio and EGEr significantly decreased ( P < 0.05) during follow-up of acute fulminant myocarditis. Conclusion Comprehensive CMR may serve as a powerful tool in children with suspected AMC. CMR in assessment of CMC may be valuable, but it is not satisfactory.
Funder
Shandong Provincal Key Research and Development Program
Subject
Radiology Nuclear Medicine and imaging,General Medicine,Radiological and Ultrasound Technology
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献