Author:
Merikanto J.,Hietala S.-O.,Lithner F.,Hägg E.,Päivänsalo M.
Abstract
Microangiographic and conventional histopathologic investigations of the kidney were compared in 15 alloxan diabetic and 7 nondiabetic control rats. Contrary to the relatively sparse histologic lesions, microangiography disclosed advanced vascular abnormalities, including arteriolar aneurysms, which increased with the duration of diabetes. It is concluded that microangiography is a sensitive and suitable method for studying the development of microvascular lesions of the kidney in experimental diabetes.
Subject
Radiology Nuclear Medicine and imaging,General Medicine,Radiological and Ultrasound Technology