Five Antiretroviral Drug Class–Resistant HIV-1 in a Treatment-Naïve Patient Successfully Suppressed with Optimized Antiretroviral Drug Selection-Reference-Cited by-同舟云学术

Five Antiretroviral Drug Class–Resistant HIV-1 in a Treatment-Naïve Patient Successfully Suppressed with Optimized Antiretroviral Drug Selection

Published:2015-07-17 Issue:5 Volume:14 Page:398-401
ISSN:2325-9582
Container-title:Journal of the International Association of Providers of AIDS Care (JIAPAC)
language:en
Short-container-title:J Int Assoc Provid AIDS Care

Author:

Volpe Joseph M.¹,Ward Douglas J.²,Napolitano Laura¹,Phung Pham¹,Toma Jonathan¹,Solberg Owen¹,Petropoulos Christos J.¹,Walworth Charles M.¹

Affiliation:

1. Monogram Biosciences, South San Francisco, CA, USA

2. Dupont Circle Physicians Group, Washington, DC, USA

Abstract

Transmitted HIV-1 exhibiting reduced susceptibility to protease and reverse transcriptase inhibitors is well documented but limited for integrase inhibitors and enfuvirtide. We describe here a case of transmitted 5 drug class–resistance in an antiretroviral (ARV)-naïve patient who was successfully treated based on the optimized selection of an active ARV drug regimen. The value of baseline resistance testing to determine an optimal ARV treatment regimen is highlighted in this case report.

Publisher

SAGE Publications

Subject

Infectious Diseases,Dermatology,Immunology

Link

http://journals.sagepub.com/doi/pdf/10.1177/2325957415596229

Reference13 articles.

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3. Transmitted raltegravir resistance in an HIV-1 CRF_AG-infected patient

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