AIDS-Associated Cardiac Lymphoma—A Review

Author:

Bush Larry M.12,Urrutia Jose G.3,Rodriguez Eduardo A.3,Perez Maria T.4

Affiliation:

1. Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA

2. University of Miami–Miller School of Medicine, JFK Medical Center, Palm Beach County, FL, USA

3. Internal Medicine, University of Miami–Miller School of Medicine, JFK Medical Center, Palm Beach County, FL, USA

4. Division of Pathology and Laboratory Medicine, Integrated Regional Laboratory Pathology Services, JFK Medical Center, Palm Beach County, FL, USA

Abstract

Despite treatment with potent and effective combination antiretroviral medications, the incidence of non-Hodgkin lymphoma (NHL) in the population living with HIV/AIDS remains significantly higher than that in noninfected individuals. The majority of the HIV-infected patients with NHL present with advanced stage extranodal disease of the B-cell phenotype. Lymphomas are the second most common tumors involving the heart in HIV-infected patients. Although the heart may serve as the primary focus of the lymphoma, in most HIV-related cases, cardiac lymphomatous involvement is part of a metastatic process that originated elsewhere.

Publisher

SAGE Publications

Subject

Infectious Diseases,Dermatology,Immunology

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