Spinal Fixation Device: A 6-Year Postimplantation Study-Reference-Cited by-同舟云学术

Spinal Fixation Device: A 6-Year Postimplantation Study

Published:2003-10 Issue:2 Volume:18 Page:109-121
ISSN:0885-3282
Container-title:Journal of Biomaterials Applications
language:en
Short-container-title:J Biomater Appl

Author:

Mohanty Mira¹,Baby Sulekha²,Menon K. V.³

Affiliation:

1. Division of Implant Biology Biomedical Technology Wing Sree Chitra Tirunal Institute for Medical Sciences and Technology Thiruvananthapuram, Kerala - 695 012, India,

2. Division of Implant Biology Biomedical Technology Wing Sree Chitra Tirunal Institute for Medical Sciences and Technology Thiruvananthapuram, Kerala - 695 012, India

3. Department of Orthopedics Amritha Institute of Medical Sciences and Research Centre Kochi, Kerala, India

Abstract

Long-term tissue response to a metal device is described here. The components of a spinal fixation device were removed 6 years after implantation, following the need for revision surgery after a fall. Scanning electron microscopy (SEM) revealed changes in surface topography of the metal. Examination of the adjacent tissue showed a chronic inflammatory response with occasional metal debris. Immunohistochemistry identified the predominant macrophages and abundant neovascularization. The presence of macrophages in tissues adjacent to the implants, in an otherwise asymptomatic person, is noteworthy.

Publisher

SAGE Publications

Subject

Biomedical Engineering,Biomaterials

Link

http://journals.sagepub.com/doi/pdf/10.1177/088532803034746

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