Anti-Neutrophil Cytoplasmic Antibody-Associated Glomerulonephritis and Malignancy: A Case of a Patient Diagnosed with Renal Failure and Pulmonary Carcinoma Concurrently

Author:

Asakura Maki1,Akimoto Tetsu12ORCID,Ohara Ken1,Masuda Takahiro1,Ono Yuko3,Saito Osamu1,Nagata Daisuke1

Affiliation:

1. Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan

2. Department of Chronic Kidney Disease Pathophysiology, Jichi Medical University, Tochigi

3. Department of Pathology, Dokkyo Medical University Saitama Medical Center, Saitama, Japan

Abstract

A 70-year-old man presented with proteinuria, microscopic hematuria, and an increased level of serum creatinine. A systemic workup revealed that the patient had bronchogenic carcinoma and anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis concurrently. Despite the increase in the cumulative number of publications on paraneoplastic glomerulopathies, an awareness of the link between cancer and ANCA-associated glomerulonephritis is lacking. We strongly recommend the accumulation of more cases similar to our own, thereby allowing us to clarify the management strategies as well as the nature of this disease condition more precisely.

Funder

Grant-in-Aid for Research on Advanced Chronic Kidney Disease, Practical Research Project for Renal Diseases from the Japan Agency for Medical Research and Development

grant for Private University Research Branding Project from the Ministry of Education, Science and Culture, Japan.

Publisher

SAGE Publications

Subject

General Medicine

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