Sustainable education and training in laboratory animal science and ethics in low- and middle-income countries in Africa – challenges, successes, and the way forward

Author:

Mohr Bert J123ORCID,Souilem Ouajdi4ORCID,Abdussamad Abdussamad M5,Benmouloud Abelouafi678ORCID,Bugnon Phillippe9,Chipangura John K1ORCID,Fahmy Sohair R10,Fourie Tamsyn1112ORCID,Gaafar Khadiga10,Jillani Ngalla E13,Kantyok Josiah T14ORCID,Martin Louise F915ORCID,Mokopasetso Mokganedi16,Mugisha Lawrence17,Nyachieo Atunga13ORCID,Lewis David I1819ORCID

Affiliation:

1. Centre for Animal Research, Faculty of Health Sciences, University of Cape Town, South Africa

2. Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa

3. Scientific Veterinary Consulting Inc., South Africa

4. Laboratory of Physiology and Pharmacology, National School of Veterinary Medicine, University of Manouba, Tunisia

5. Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, Bayero University, Nigeria

6. Department of Biology and Physiology of Organism, Houari Boumedienne University of Sciences and Technology, Algeria

7. Department of Biology, University of M’hamed Bougara Boumerdes, Algeria

8. Department of Nature and Life Sciences, University of Algiers 1, Algeria

9. Institute of Laboratory Animal Science, University of Zürich, Switzerland

10. Zoology Department, Faculty of Science, Cairo University, Egypt

11. LAS Veterinary Consultancy, South Africa

12. South African Association for Laboratory Animal Science (SAALAS), South Africa

13. Institute of Primate Research, Kenya

14. Johan Vet Network, Nigeria

15. Clinic for Zoo Animals, Exotic Pets and Wildlife, University of Zurich, Switzerland

16. Botswana Vaccine Institute, Botswana

17. College of Veterinary Medicine, Animal Resources and Biosecurity (COVAB), Makerere University, Uganda

18. School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, UK

19. International Union of Basic and Clinical Pharmacology-Integrative and Organ Systems Pharmacology Initiative (IUPHAR IOSP)

Abstract

Despite the recognised need for education and training in laboratory animal science (LAS) and ethics in Africa, access to such opportunities has historically been limited. To address this, the Pan-African Network for Laboratory Animal Science and Ethics (PAN-LASE) was established to pioneer a support network for the development of education and training in LAS and ethics across the African continent. In the 4.5 years since the establishment of PAN-LASE, 3635 individuals from 28 African countries have participated in our educational activities. Returning to their home institutions, they have both established and strengthened institutional and regional hubs of knowledge and competence across the continent. Additionally, PAN-LASE supported the development of guidelines for establishment of institutional Animal Ethics Committees, a critical step in the implementation of ethical review processes across the continent, and in enhancing animal welfare and scientific research standards. Key challenges and opportunities for PAN-LASE going forward include the formalisation of the network; the sustainability of education and training programmes; implementation of effective hub-and-spoke models of educational provision; strengthening governance frameworks at institutional, national and regional levels; and the availability of Africa-centric open access educational resources. Our activities are enhancing animal welfare and the quality of animal research undertaken across Africa, enabling African researchers to undertake world-leading research to offer solutions to the challenges facing the continent. The challenges, successes and the lessons learnt from PAN-LASE’s journey are applicable to other low- and middle-income countries across the world seeking to enhance animal welfare, research ethics and ethical review in their own country or region.

Publisher

SAGE Publications

Subject

General Veterinary,Animal Science and Zoology

Reference40 articles.

1. Animal Experimentation in Africa: Legislation and Guidelines

2. South African Bureau of Standards. South African National Standard: The care and use of animals for scientific purposes (SANS 10386:2021). 2nd ed. Groenkloof, South Africa: South African Bureau of Standards, 2021, p.324.

3. Government of Kenya. Prevention of Cruelty to Animals Act, 1962. Chapter 360 of the Laws of Kenya.

4. Government of Kenya. Veterinary Surgeons and Veterinary Paraprofessionals Act, 2011. Chapter 366 of the Laws of Kenya.

5. Consortium for National Health Research. National guidelines for the care and use of animals in research and education in Kenya, http://www.keshop.co.ke/cnhr1/national-guidelines-for-the-care-use-of-animals-in-research-education-in-kenya/ (2014, accessed 29 June 2020).

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