Rats prefer condensed milk to strawberry jam – a new possibility for voluntary oral drug administration

Author:

Ferreira-Duarte Mariana12ORCID,Lopes Igor Moreira,Morato Manuela12ORCID,Duarte-Araújo Margarida23ORCID

Affiliation:

1. Laboratory of Pharmacology, Department of Drug Sciences, Faculty of Pharmacy of the University of Porto (FFUP), Portugal

2. LAQV@REQUIMTE, University of Porto, Portugal

3. Department of Immuno-Physiology and Pharmacology, School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Portugal

Abstract

Voluntary oral drug administration using sweet substances promotes rodents’ therapeutic compliance while reducing stress induced by forced drug administration. We aimed to test whether rats would willingly eat strawberry jam or condensed milk from a syringe, and which one they would prefer. Our results show that rats prefer condensed milk, demonstrating its potential as a vehicle for the voluntary oral administration of drugs in experimental protocols.

Funder

Fundação para a Ciência e Tecnologia

Publisher

SAGE Publications

Subject

General Veterinary,Animal Science and Zoology

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