Feeding management before gastrointestinal studies in pigs

Author:

Gregson Rachael1ORCID,Greenhalgh Stephen1,Cox Benjamin2,Cochrane Sandy3,Clutton R Eddie1

Affiliation:

1. Wellcome Critical Care Laboratory for Large Animals, Dryden Farm, University of Edinburgh, UK

2. Division of Imaging and Technology, School of Medicine, University of Dundee, UK

3. James Watt South Building, James Watt School of Engineering, University of Glasgow, UK

Abstract

Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.

Funder

UK Engineering and Physical Sciences Research Council

Wellcome Trust Biomedical Resource Grant

Publisher

SAGE Publications

Subject

General Veterinary,Animal Science and Zoology

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Anesthesia and analgesia in laboratory pigs;Anesthesia and Analgesia in Laboratory Animals;2023

2. Smart pills for gastrointestinal diagnostics and therapy;Advanced Drug Delivery Reviews;2021-10

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